oxidative stress
Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
January 11, 2013 Publications, Featured
T Shimazu, MD Hirschey, J Newman, W He, K Shirakawa, N Le Moan, CA Grueter, H Lim, LR Saunders, RD Stevens, CB Newgard, RV Farese Jr., R de Cabo, S Ulrich, K Akassoglou, E Verdin (2012) Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor. Science, 2013 Jan 11;339(6116):211-4Read More...SIRT3 Weighs Heavily in the Metabolic Balance: A New Role for SIRT3 in Metabolic Syndrome
February 01, 2013 Publications, Perspective
Michelle F Green and Matthew D Hirschey (2012) SIRT3 Weighs Heavily in the Metabolic Balance: A New Role for SIRT3 in Metabolic Syndrome. Journal of Gerontology: Biological Science. 2013 68(2):105-7.Read More...
SIRT3 Regulates Mitochondrial Protein Acetylation and Intermediary Metabolism
December 31, 2011 Publications, Review
MD Hirschey, T Shimazu, J-Y Huang, B Schwer, and E Verdin (2011) SIRT3 Regulates Mitochondrial Protein Acetylation and Intermediary Metabolism. Metabolism and Disease (Cold Spring Harbor Symposia on Quantitative Biology) 76: 267-77Read More...
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
December 01, 2010 Publications
Qiu X, Brown K, Hirschey MD, Verdin E, Chen D. (2010) Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab. Dec 1;12(6):662-7.Read More...
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
August 22, 2011 Publications
Enxuan Jing, Brice Emanuelli, Matthew D. Hirschey, Jeremie Boucher, Kevin Y. Lee, David Lombard, Eric M. Verdin, and C. Ronald Kahn (2011) Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. PNAS, In pressRead More...