mitochondria
HINT2 and Fatty Liver Disease: Mitochondrial Protein Hyperacetylation Gives A Hint?
September 18, 2012 Publications, Perspective
KA Anderson*, D Wang* and MD Hirschey. HINT2 and Fatty Liver Disease: Mitochondrial Protein Hyperacetylation Gives A Hint? Hepatology (2012) In pressRead More...Mitochondrial protein acetylation regulates metabolism
June 01, 2012 Publications
KA Anderson and MD Hirschey (2012) Mitochondrial protein acetylation regulates metabolism. Essays in Biochemistry, 52:23-35.Read More...SIRT3 Regulates Mitochondrial Protein Acetylation and Intermediary Metabolism
December 31, 2011 Publications, Review
MD Hirschey, T Shimazu, J-Y Huang, B Schwer, and E Verdin (2011) SIRT3 Regulates Mitochondrial Protein Acetylation and Intermediary Metabolism. Metabolism and Disease (Cold Spring Harbor Symposia on Quantitative Biology) 76: 267-77Read More...
SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome
August 18, 2011 Publications, Featured
MD Hirschey, T Shimazu, E Jing, CA Grueter, AM Collins, B Aouizerat, A Stančáková, E Goetzman, MM Lam, B Schwer, RD Stevens, MJ Muehlbauer, S Kakar, NM Bass, J Kuusisto, M Laakso, FW Alt, CB Newgard, RV Farese Jr., CR Kahn and E Verdin (2011) SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome. Molecular Cell, In pressRead More...
Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling
September 20, 2010 Publications, Review
Verdin E, Hirschey MD, Finley LW, Haigis MC. (2010) Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling. Trends Biochem Sci. Dec;35(12):669-75. Epub 2010 Sep 20.Read More...
Acetate metabolism and aging: An emerging connection
May 15, 2010 Publications, Review
Shimazu T, Hirschey MD, Huang JY, Ho LT, Verdin E. (2010) Acetate metabolism and aging: An emerging connection. Mech Ageing Dev. Jul-Aug;131(7-8):511-6. Epub 2010 May 15.Read More...SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
March 04, 2010 Publications, Featured
Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV Jr, Alt FW, Kahn CR, Verdin E. (2010) SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature, 464, 121-125Read More...Mitochondrial Sirtuins
January 07, 2010 Publications, Review
Huang JY, Hirschey MD, Shimazu T, Ho L, Verdin E. (2010) Mitochondrial Sirtuins. Biochim Biophys Acta. 2010 Jan 7.Read More...
Acetylation of mitochondrial proteins
May 06, 2009 Publications, Methods
Hirschey MD, Shimazu T, Huang JY, Verdin E. (2009) Acetylation of mitochondrial proteins. Methods Enzymol. 2009;457:137-47.Read More...
Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation
October 08, 2007 Publications
Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV Jr, Weisssman S, Verdin E, Schwer B (2007). Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation. Mol. Cell Biol. Epub Oct. 8Read More...