SIRT3 Weighs Heavily in the Metabolic Balance: A New Role for SIRT3 in Metabolic Syndrome

blogEntryThumbnailMichelle F Green and Matthew D Hirschey (2012) SIRT3 Weighs Heavily in the Metabolic Balance: A New Role for SIRT3 in Metabolic Syndrome. Journal of Gerontology: Biological Science. 2013 68(2):105-7.

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Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice

blogEntryThumbnailRyan S. Streeper*, Carrie A. Grueter*, Nathan Salomonis, Sylvaine Cases, Malin C. Levin, Suneil K. Koliwad, Ping Zhou, Matthew D. Hirschey, Eric Verdin, and Robert V. Farese, Jr. (2012) Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice. Aging, 4 (1), 13-27
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Acetate metabolism and aging: An emerging connection

blogEntryThumbnailShimazu T, Hirschey MD, Huang JY, Ho LT, Verdin E. (2010) Acetate metabolism and aging: An emerging connection. Mech Ageing Dev. Jul-Aug;131(7-8):511-6. Epub 2010 May 15.Read More...

Mitochondrial Sirtuins

blogEntryThumbnailHuang JY, Hirschey MD, Shimazu T, Ho L, Verdin E. (2010) Mitochondrial Sirtuins. Biochim Biophys Acta. 2010 Jan 7.
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Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation

blogEntryThumbnailLombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV Jr, Weisssman S, Verdin E, Schwer B (2007). Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation. Mol. Cell Biol. Epub Oct. 8Read More...