SIRT3 Regulates Mitochondrial Protein Acetylation and Intermediary Metabolism

blogEntryThumbnailMD Hirschey, T Shimazu, J-Y Huang, B Schwer, and E Verdin (2011) SIRT3 Regulates Mitochondrial Protein Acetylation and Intermediary Metabolism. Metabolism and Disease (Cold Spring Harbor Symposia on Quantitative Biology) 76: 267-77
Read More...

SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production

blogEntryThumbnailShimazu T, Hirschey MD, Hua L, Dittenhafer-Reed KE, Schwer B, Lombard DB, Li Y, Bunkenborg J, Alt FW, Denu JM, Jacobson MP, Verdin E. (2010) SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. Cell Metab. Dec 1;12(6):654-61.Read More...

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

blogEntryThumbnailHirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV Jr, Alt FW, Kahn CR, Verdin E. (2010) SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature, 464, 121-125Read More...