acetylation
Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
January 11, 2013 Publications, Featured
T Shimazu, MD Hirschey, J Newman, W He, K Shirakawa, N Le Moan, CA Grueter, H Lim, LR Saunders, RD Stevens, CB Newgard, RV Farese Jr., R de Cabo, S Ulrich, K Akassoglou, E Verdin (2012) Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor. Science, 2013 Jan 11;339(6116):211-4Read More...HINT2 and Fatty Liver Disease: Mitochondrial Protein Hyperacetylation Gives A Hint?
September 18, 2012 Publications, Perspective
KA Anderson*, D Wang* and MD Hirschey. HINT2 and Fatty Liver Disease: Mitochondrial Protein Hyperacetylation Gives A Hint? Hepatology (2012) In pressRead More...Mitochondrial protein acetylation regulates metabolism
June 01, 2012 Publications
KA Anderson and MD Hirschey (2012) Mitochondrial protein acetylation regulates metabolism. Essays in Biochemistry, 52:23-35.Read More...SIRT3 Weighs Heavily in the Metabolic Balance: A New Role for SIRT3 in Metabolic Syndrome
February 01, 2013 Publications, Perspective
Michelle F Green and Matthew D Hirschey (2012) SIRT3 Weighs Heavily in the Metabolic Balance: A New Role for SIRT3 in Metabolic Syndrome. Journal of Gerontology: Biological Science. 2013 68(2):105-7.Read More...
SIRT3 Regulates Mitochondrial Protein Acetylation and Intermediary Metabolism
December 31, 2011 Publications, Review
MD Hirschey, T Shimazu, J-Y Huang, B Schwer, and E Verdin (2011) SIRT3 Regulates Mitochondrial Protein Acetylation and Intermediary Metabolism. Metabolism and Disease (Cold Spring Harbor Symposia on Quantitative Biology) 76: 267-77Read More...
SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome
August 18, 2011 Publications, Featured
MD Hirschey, T Shimazu, E Jing, CA Grueter, AM Collins, B Aouizerat, A Stančáková, E Goetzman, MM Lam, B Schwer, RD Stevens, MJ Muehlbauer, S Kakar, NM Bass, J Kuusisto, M Laakso, FW Alt, CB Newgard, RV Farese Jr., CR Kahn and E Verdin (2011) SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome. Molecular Cell, In pressRead More...
Acetylation of mitochondrial proteins
May 06, 2009 Publications, Methods
Hirschey MD, Shimazu T, Huang JY, Verdin E. (2009) Acetylation of mitochondrial proteins. Methods Enzymol. 2009;457:137-47.Read More...
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
August 22, 2011 Publications
Enxuan Jing, Brice Emanuelli, Matthew D. Hirschey, Jeremie Boucher, Kevin Y. Lee, David Lombard, Eric M. Verdin, and C. Ronald Kahn (2011) Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. PNAS, In pressRead More...