http://lab.hirschey.org/index.htmlPublicationsenmatthew.hirschey@duke.eduCopyright 2011 Matthew Hirschey2013-01-11T12:00:00-05:00 hourly 1 2000-01-01T12:00+00:00 Sat, 23 Feb 2013 14:04:41 -0500matthew.hirschey@duke.eduPublicationsFeatured2013-01-11T12:00:00-05:00http://lab.hirschey.org/publications/files/science2012.html#unique-entry-id-23http://lab.hirschey.org/publications/files/science2012.html#unique-entry-id-23T Shimazu, MD Hirschey, J Newman, W He, K Shirakawa, N Le Moan, CA Grueter, H Lim, LR Saunders, RD Stevens, CB Newgard, RV Farese Jr., R de Cabo, S Ulrich, K Akassoglou, E Verdin (2012) Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor. Science, 2013 Jan 11;339(6116):211-4]]>matthew.hirschey@duke.eduPublications2013-02-01T12:00:00-05:00http://lab.hirschey.org/publications/files/naturechembiol2012.html#unique-entry-id-22http://lab.hirschey.org/publications/files/naturechembiol2012.html#unique-entry-id-22P Gut, B Baeza-Raja, O Andersson, L Hasenkamp, D Hesselson, K Akassoglou, E Verdin, MD Hirschey and DYR Stainier. Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism. Nature Chem. Biol. (2013) 9, 97–104]]>matthew.hirschey@duke.eduPublicationsPerspective2012-09-18T12:00:00-04:00http://lab.hirschey.org/publications/files/hepatology2012.html#unique-entry-id-21http://lab.hirschey.org/publications/files/hepatology2012.html#unique-entry-id-21KA Anderson*, D Wang* and MD Hirschey. HINT2 and Fatty Liver Disease: Mitochondrial Protein Hyperacetylation Gives A Hint? Hepatology (2012) In press]]>matthew.hirschey@duke.eduPublications2012-06-01T12:00:00-04:00http://lab.hirschey.org/publications/files/eib2012.html#unique-entry-id-20http://lab.hirschey.org/publications/files/eib2012.html#unique-entry-id-20KA Anderson and MD Hirschey (2012) Mitochondrial protein acetylation regulates metabolism. Essays in Biochemistry, 52:23-35.]]>matthew.hirschey@duke.eduPublications2012-06-06T12:00:00-04:00http://lab.hirschey.org/publications/files/cellmetab2012.html#unique-entry-id-19http://lab.hirschey.org/publications/files/cellmetab2012.html#unique-entry-id-19Joel T. Haas, Ji Miao, Dipanjan Chanda, Yanning Wang, Enpeng Zhao, Mary E. Haas, Matthew Hirschey, B. Vaitheesvaran, Robert V. Farese, Irwin J. Kurland, Mark Graham, Rosanne Crooke, Fabienne Foufelle, Sudha B. Biddinger (2012) Hepatic Insulin Signaling Is Required for Obesity-Dependent Expression of SREBP-1c mRNA but Not for Feeding-Dependent Expression. Cell Metab. Jun 6;15(6):873.]]>matthew.hirschey@duke.eduPublicationsPerspective2013-02-01T12:00:00-05:00http://lab.hirschey.org/publications/files/jgbs2012.html#unique-entry-id-17http://lab.hirschey.org/publications/files/jgbs2012.html#unique-entry-id-17Michelle F Green and Matthew D Hirschey (2012) SIRT3 Weighs Heavily in the Metabolic Balance: A New Role for SIRT3 in Metabolic Syndrome. Journal of Gerontology: Biological Science. 2013 68(2):105-7.

]]>matthew.hirschey@duke.eduPublications2012-01-29T12:00:00-05:00http://lab.hirschey.org/publications/files/aging2012.html#unique-entry-id-16http://lab.hirschey.org/publications/files/aging2012.html#unique-entry-id-16Ryan S. Streeper*, Carrie A. Grueter*, Nathan Salomonis, Sylvaine Cases, Malin C. Levin, Suneil K. Koliwad, Ping Zhou, Matthew D. Hirschey, Eric Verdin, and Robert V. Farese, Jr. (2012) Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice. Aging, 4 (1), 13-27
]]>matthew.hirschey@duke.eduPublicationsPerspectiveFeatured2011-12-07T12:00:00-05:00http://lab.hirschey.org/publications/files/cellmetab2011.html#unique-entry-id-15http://lab.hirschey.org/publications/files/cellmetab2011.html#unique-entry-id-15Hirschey MD (2011) Old Enzymes, New Tricks: Sirtuins Are NAD(+)-Dependent De-acylases. Cell Metab. Dec 7;14(6):718.]]>matthew.hirschey@duke.eduPublicationsReview2011-12-31T12:00:00-05:00http://lab.hirschey.org/publications/files/cshl2011.html#unique-entry-id-11http://lab.hirschey.org/publications/files/cshl2011.html#unique-entry-id-11MD Hirschey, T Shimazu, J-Y Huang, B Schwer, and E Verdin (2011) SIRT3 Regulates Mitochondrial Protein Acetylation and Intermediary Metabolism. Metabolism and Disease (Cold Spring Harbor Symposia on Quantitative Biology) 76: 267-77
]]>matthew.hirschey@duke.eduPublicationsFeatured2011-08-18T12:00:00-04:00http://lab.hirschey.org/publications/files/molcell2011.html#unique-entry-id-10http://lab.hirschey.org/publications/files/molcell2011.html#unique-entry-id-10MD Hirschey, T Shimazu, E Jing, CA Grueter, AM Collins, B Aouizerat, A Stančáková, E Goetzman, MM Lam, B Schwer, RD Stevens, MJ Muehlbauer, S Kakar, NM Bass, J Kuusisto, M Laakso, FW Alt, CB Newgard, RV Farese Jr., CR Kahn and E Verdin (2011) SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome. Molecular Cell, In press
]]>matthew.hirschey@duke.eduPublicationsPerspective2011-06-19T13:00:00-04:00http://lab.hirschey.org/publications/files/aging2011.html#unique-entry-id-9http://lab.hirschey.org/publications/files/aging2011.html#unique-entry-id-9MD Hirschey*, T Shimazu*, JA Capra*, KS Pollard, and E Verdin. (2011) SIRT1 and SIRT3 Deacetylate Homologous Substrates: AceCS1,2 and HMGCS1,2. AGING 3, 1–8

]]>matthew.hirschey@duke.eduPublications2010-12-01T15:00:01-05:00http://lab.hirschey.org/publications/files/cellmetab2010b.html#unique-entry-id-8http://lab.hirschey.org/publications/files/cellmetab2010b.html#unique-entry-id-8Qiu X, Brown K, Hirschey MD, Verdin E, Chen D. (2010) Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab. Dec 1;12(6):662-7.
]]>matthew.hirschey@duke.eduPublicationsFeatured2010-12-01T15:00:00-05:00http://lab.hirschey.org/publications/files/cellmetab2010a.html#unique-entry-id-7http://lab.hirschey.org/publications/files/cellmetab2010a.html#unique-entry-id-7Shimazu T, Hirschey MD, Hua L, Dittenhafer-Reed KE, Schwer B, Lombard DB, Li Y, Bunkenborg J, Alt FW, Denu JM, Jacobson MP, Verdin E. (2010) SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. Cell Metab. Dec 1;12(6):654-61.]]>matthew.hirschey@duke.eduPublicationsReview2010-09-20T15:00:00-04:00http://lab.hirschey.org/publications/files/tibs2010.html#unique-entry-id-6http://lab.hirschey.org/publications/files/tibs2010.html#unique-entry-id-6Verdin E, Hirschey MD, Finley LW, Haigis MC. (2010) Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling. Trends Biochem Sci. Dec;35(12):669-75. Epub 2010 Sep 20.
]]>matthew.hirschey@duke.eduPublicationsReview2010-05-15T15:00:00-04:00http://lab.hirschey.org/publications/files/mad2010.html#unique-entry-id-5http://lab.hirschey.org/publications/files/mad2010.html#unique-entry-id-5Shimazu T, Hirschey MD, Huang JY, Ho LT, Verdin E. (2010) Acetate metabolism and aging: An emerging connection. Mech Ageing Dev. Jul-Aug;131(7-8):511-6. Epub 2010 May 15.]]>matthew.hirschey@duke.eduPublicationsFeatured2010-03-04T15:00:00-05:00http://lab.hirschey.org/publications/files/nature2010.html#unique-entry-id-4http://lab.hirschey.org/publications/files/nature2010.html#unique-entry-id-4Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV Jr, Alt FW, Kahn CR, Verdin E. (2010) SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature, 464, 121-125]]>matthew.hirschey@duke.eduPublicationsReview2010-01-07T15:00:00-05:00http://lab.hirschey.org/publications/files/bba2010.html#unique-entry-id-3http://lab.hirschey.org/publications/files/bba2010.html#unique-entry-id-3Huang JY, Hirschey MD, Shimazu T, Ho L, Verdin E. (2010) Mitochondrial Sirtuins. Biochim Biophys Acta. 2010 Jan 7.
]]>matthew.hirschey@duke.eduPublicationsMethods2009-05-06T15:00:00-04:00http://lab.hirschey.org/publications/files/mie2009.html#unique-entry-id-2http://lab.hirschey.org/publications/files/mie2009.html#unique-entry-id-2Hirschey MD, Shimazu T, Huang JY, Verdin E. (2009) Acetylation of mitochondrial proteins. Methods Enzymol. 2009;457:137-47.
]]>matthew.hirschey@duke.eduPublications2007-10-08T15:00:00-04:00http://lab.hirschey.org/publications/files/mcb2007.html#unique-entry-id-1http://lab.hirschey.org/publications/files/mcb2007.html#unique-entry-id-1Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV Jr, Weisssman S, Verdin E, Schwer B (2007). Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation. Mol. Cell Biol. Epub Oct. 8]]>matthew.hirschey@duke.eduPublications2006-05-25T15:00:00-04:00http://lab.hirschey.org/publications/files/jbic2006.html#unique-entry-id-0http://lab.hirschey.org/publications/files/jbic2006.html#unique-entry-id-0Hirschey MD, Han YJ, Stucky GD, Butler A. (2006) Imaging Escherichia coli using functionalized core/shell CdSe/CdS quantum dots. J. Bio. Inorg. Chem. Jul;11(5):663-9. Epub 2006 May 25.
]]>matthew.hirschey@duke.eduPublications2011-08-22T12:00:00-04:00http://lab.hirschey.org/publications/files/pnas2011.html#unique-entry-id-14http://lab.hirschey.org/publications/files/pnas2011.html#unique-entry-id-14Enxuan Jing, Brice Emanuelli, Matthew D. Hirschey, Jeremie Boucher, Kevin Y. Lee, David Lombard, Eric M. Verdin, and C. Ronald Kahn (2011) Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. PNAS, In press]]>matthew.hirschey@duke.eduPublications2012-03-02T12:00:00-05:00http://lab.hirschey.org/publications/files/jpr2012.html#unique-entry-id-18http://lab.hirschey.org/publications/files/jpr2012.html#unique-entry-id-18Kristofer S Fritz, James Joseph Galligan, Matthew Hirschey, Eric Verdin, and Dennis R. Petersen (2012) Mitochondrial Acetylome Analysis in a Mouse Model of Alcohol-Induced Liver Injury Utilizing SIRT3 Knockout Mice. Journal of Proteome Research. 2012 11(3):1633-43.
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