Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation

blogEntryThumbnailQiu X, Brown K, Hirschey MD, Verdin E, Chen D. (2010) Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab. Dec 1;12(6):662-7.
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SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production

blogEntryThumbnailShimazu T, Hirschey MD, Hua L, Dittenhafer-Reed KE, Schwer B, Lombard DB, Li Y, Bunkenborg J, Alt FW, Denu JM, Jacobson MP, Verdin E. (2010) SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. Cell Metab. Dec 1;12(6):654-61.Read More...